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Use of Stopped-Flow Fluorescence and Labeled Nucleotides to Analyze the ATP Turnover Cycle of Kinesins
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Permeabilidad mitocondrial: doble función para el translocator ADP/ATP?

Andrew P Halestrap1

  • 1Department of Biochemistry, University of Bristol, Bristol BS8 1TD, UK. a.halestrap@bristol.ac.uk

Nature
|August 31, 2004
PubMed
Resumen

La translocación del nucleótido de adenina (ANT) puede no ser esencial para la formación del poro de transición de permeabilidad mitocondrial (mtPTP). Las mitocondrias del hígado del ratón ANT-knockout todavía exhiben actividad mtPTP, lo que sugiere que la ANT es indispensable para la muerte celular.

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