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Updated: Jul 6, 2026

Assays for the Degradation of Misfolded Proteins in Cells
10:56

Assays for the Degradation of Misfolded Proteins in Cells

Published on: August 28, 2016

Deterioro de la degradación de la alfa-sinucleína mutante por la autofagia mediada por chaperonas

Ana Maria Cuervo1, Leonidas Stefanis, Ross Fredenburg

  • 1Department of Anatomy and Structural Biology, Marion Bessin Liver Research Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA. amcuervo@aecom.yu.edu

Science (New York, N.Y.)
|August 31, 2004
PubMed
Resumen

La alfa-sinucleína de tipo salvaje se degrada a través de la autofagia mediada por la chaperona. Los mutantes patógenos bloquean esta vía, causando potencialmente la toxicidad de la enfermedad de Parkinson.

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