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Cromatografía de permeación de gel como método de cribado combinatorio: identificación de catalizadores de

Andrew F Mason¹, Geoffrey W Coates

¹Department of Chemistry and Chemical Biology, Baker Laboratory, Cornell University, Ithaca, NY 14853, USA.

Journal of the American Chemical Society

|September 2, 2004

Resumen

Los catalizadores de titanio altamente activos para la producción de polipropileno se identificaron mediante un método de cribado combinatorio. Los catalizadores de ligandos mixtos con un solo ligando orto-fluorado demostraron un rendimiento superior en la polimerización sindiospecífica.

Área de la Ciencia:

Química de Polímeros La Química de Polímeros es la química de los polímeros.
Catálisis organometálica por catálisis orgánica.

Sus antecedentes:

Los complejos de titanio bis ((phenoxyimine) son catalizadores cruciales en la polimerización de las olefinas.
La optimización de la estructura del catalizador es clave para controlar las propiedades y la actividad del polímero.

Objetivo del estudio:

Para examinar una biblioteca de catalizadores de titanio de ligando mixto bis ((phenoxyimine) para la polimerización del propileno.
Para identificar catalizadores altamente activos para la síntesis de polipropileno sindiospecífico.

Principales métodos:

Selección combinatoria agrupada de las bibliotecas de catalizadores.
Cromatografía por permeación de gel (GPC) para el análisis de polímeros.
La polimerización sindiospecífica del propileno.

Principales resultados:

Identificación de catalizadores de titanio de ligando mixto y ligando de alta actividad.
Los complejos de ligandos mixtos con un ligando orto-fluorado superaron a los análogos homoligados.
Se ha demostrado una mayor actividad en la polimerización sindiospecífica.

Conclusiones:

Los catalizadores de titanio de ligando mixto bis ((phenoxyimine) ofrecen un mejor rendimiento que los sistemas homoligados.
La colocación estratégica de los ligandos fluorados mejora significativamente la actividad y la selectividad del catalizador.
Este trabajo proporciona una vía para el desarrollo de catalizadores de polipropileno de próxima generación.

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