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La unión de la distamicina A al ADN dañado por los rayos UV

Aki Inase1, Takashi S Kodama, Jafar Sharif

  • 1Contribution from the Division of Chemistry, Graduate School of Engineering Science, Osaka University, 1-3 Machikaneyama, Toyonaka, Osaka 560-8531, Japan.

Journal of the American Chemical Society
|September 2, 2004
PubMed
Resumen

La distamicina A se une al ADN dañado por los rayos UV que contiene (6-4) fotoproductos, alterando la estequiometría de unión. Esta unión específica contrasta con su incapacidad para asociarse con los dímeros de pirimidina del ciclobutano.

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