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In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells
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Regulación de la supervivencia de las células B por medio de la señalización nuclear mediada por PKCdelta dependiente

Ingrid Mecklenbräuker1, Susan L Kalled, Michael Leitges

  • 1Laboratory of Lymphocyte Signaling, The Rockefeller University, New York, New York 10021, USA.

Nature
|September 14, 2004
PubMed
Resumen

Los científicos descubrieron una nueva forma en que el cuerpo controla la supervivencia de las células B. La proteína quinasa Cdelta (PKCdelta) normalmente desencadena la muerte de las células B, pero BAFF previene esto, lo que podría afectar a las enfermedades autoinmunes.

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