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Updated: Jul 16, 2026

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
10:17

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations

Published on: November 3, 2010

Relación causal entre la duplicación del gen alfa-sinucleína y la enfermedad de Parkinson familiar

P Ibáñez1, A-M Bonnet, B Débarges

  • 1INSERM U289, Neurologie et Thérapeutique Expérimentale, Hôpital de la Pitié-Salpêtrière, AP-HP, Paris, France.

Lancet (London, England)
|September 29, 2004
PubMed
Resumen

Las duplicaciones en el gen alfa-sinucleína (SNCA) son una causa significativa de la enfermedad de Parkinson familiar. La dosis de genes afecta la presentación de la enfermedad, con duplicaciones que conducen a los síntomas típicos de la enfermedad de Parkinson.

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