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Updated: Jul 15, 2026
14:09
Genetic Studies of Human DNA Repair Proteins Using Yeast as a Model System
Published on: March 18, 2010
Un gen humano responsable del síndrome de Zellweger que afecta el ensamblaje del peroxisoma
N Shimozawa1, T Tsukamoto, Y Suzuki
1Department of Pediatrics, Gifu University School of Medicine, Japan.
Science (New York, N.Y.)
|February 28, 1992
Resumen
El síndrome de Zellweger es causado por una alteración en el ensamblaje de los peroxisomas. Un ADN clonado complementa este defecto mediante la corrección de una mutación en el factor de ensamblaje del peroxisoma-1.
Área de la Ciencia:
- Biología celular Biología celular.
- Genética La genética.
- La bioquímica es la bioquímica.
Sus antecedentes:
- El síndrome de Zellweger es un trastorno genético grave caracterizado por el ensamblaje defectuoso de los peroxisomas.
- Los peroxisomas son orgánulos vitales involucrados en varios procesos metabólicos, y su disfunción conduce a un espectro de anormalidades clínicas.
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