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Generation of Aggregates of Mouse Embryonic Stem Cells that Show Symmetry Breaking, Polarization and Emergent Collective Behaviour In Vitro
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Aprovechando chaperones para generar inhibidores de moléculas pequeñas de la agregación beta amiloide

Jason E Gestwicki1, Gerald R Crabtree, Isabella A Graef

  • 1Department of Pathology, Howard Hughes Medical Institute, Stanford University Medical School, Stanford, CA 94305, USA.

Science (New York, N.Y.)
|October 30, 2004
PubMed
Resumen

Los investigadores desarrollaron nuevas moléculas pequeñas para inhibir la agregación beta-amiloide, un factor clave en las enfermedades neurodegenerativas. Esta estrategia se dirige a la enfermedad de Alzheimer mediante el uso de acompañantes para mejorar la efectividad de la molécula contra los grupos de proteínas.

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