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Síntesis total de (-) -disorazol C1 en su conjunto

Peter Wipf1, Thomas H Graham

  • 1Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260, USA. pwipf@pitt.edu

Journal of the American Chemical Society
|November 26, 2004
PubMed
Resumen

Los investigadores sintetizaron el disorazol C1, un producto natural antimitótico de Sorangium cellulosum. Esta síntesis estereoselectiva confirma la configuración del compuesto y demuestra un nuevo método para el manejo de macrodiolidos de polieno sensibles.

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