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Características clínicas de las deficiencias dominantes y recesivas del receptor gamma 1 de interferón

Susan E Dorman1, Capucine Picard, David Lammas

  • 1Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 10, CRC B3-419, 10 Center Drive, MSC 1684, Bethesda, MD 20892-1684, USA.

Lancet (London, England)
|December 14, 2004
PubMed
Resumen

Las deficiencias parciales recesivas completas y dominantes del receptor gamma de interferón 1 (IFNgammaR1) causan infecciones micobacterianas graves. La deficiencia recesiva se presenta con un inicio más temprano y una enfermedad más grave en comparación con la deficiencia dominante.

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