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Updated: Jun 12, 2026

Assaying the Kinase Activity of LRRK2 in vitro
06:09

Assaying the Kinase Activity of LRRK2 in vitro

Published on: January 18, 2012

Una mutación común de LRRK2 en la enfermedad idiopática de Parkinson

William P Gilks1, Patrick M Abou-Sleiman, Sonia Gandhi

  • 1Department of Molecular Neuroscience, Institute of Neurology and National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK.

Lancet (London, England)
|February 1, 2005
PubMed
Resumen

Se encontró una mutación genética común de la kinasa de repetición rica en leucina 2 (LRRK2), Gly2019Ser, en el 1,6% de los pacientes con enfermedad de Parkinson idiopática. Este hallazgo implica una sola mutación mendeliana en la enfermedad de Parkinson esporádica.

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