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Mutaciones del receptor transformador del factor de crecimiento beta y hipertensión arterial pulmonar en la infancia

Rachel E Harrison1, Rolf Berger, Sheila G Haworth

  • 1Division of Medical Genetics, University of Leicester, Leicester, UK.

Circulation
|February 3, 2005
PubMed
Resumen

Las mutaciones genéticas en los receptores transformadores del factor de crecimiento beta son una causa clave de la hipertensión arterial pulmonar (HAP) en la infancia. La HAP de inicio temprano, particularmente la HAP idiopática, a menudo involucra estos defectos genéticos, destacando una etiología heterogénea.

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