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Calcificación coronaria y su relación con la aterosclerosis extracoronaria en hombres hipercolesterolemicos
J L Megnien1, V Sene, S Jeannin
1Centre de Médecine Préventive Cardio-vasculaire, INSERM U 28, Paris, France.
Circulation
|May 1, 1992
Resumen
En pacientes con colesterol alto, la calcificación coronaria está fuertemente relacionada con las placas en otras arterias. La ecografía de estos vasos extracoronarios puede ayudar a detectar la enfermedad arterial coronaria en individuos asintomáticos.
Área de la Ciencia:
- Medicina Cardiovascular La medicina cardiovascular es una especialidad de la salud.
- Radiología Radiología.
- Imágenes médicas de imágenes médicas.
Sus antecedentes:
- Investigó la prevalencia de calcificaciones coronarias y placas extracoronarias en pacientes con hipercolesterolemia asintomática.
- Se evaluó la asociación entre la calcificación coronaria y la carga aterosclerótica extracoronaria.
Objetivo del estudio:
- Para determinar la relación entre la calcificación coronaria y las placas extracoronarias en hombres con hipercolesterolemia.
- Evaluar la utilidad de la evaluación de los vasos extracoronarios para el cribado de la aterosclerosis coronaria.
Principales métodos:
- Utilizó tomografía computarizada ultrarrápida (TC) para la puntuación del calcio coronario.
- Evaluación ecográfica realizada de las placas carótidas, aórticas y femorales en 111 hombres con hipercolesterolemia.
- Se analizó la asociación entre la calcificación coronaria (presencia / ausencia, puntuación de calcio) y la presencia de placa extracoronaria.
Principales resultados:
- El 65% de los pacientes tenían calcificación coronaria y el 72% tenían placa extracoronaria.
- La calcificación coronaria se asoció significativamente con las placas aórticas y femorales, y el número de sitios extracoronarios enfermos.
- Las puntuaciones más altas de calcio coronario se correlacionan con la presencia de placas carotídeas, aórticas y femorales, y el número de sitios enfermos.
- La presencia de dos o tres sitios extracoronarios enfermos predijo la calcificación coronaria con un 78% de potencia.
- La puntuación de calcio coronario se correlacionó con la edad y los niveles de triglicéridos.
Conclusiones:
- Existe una fuerte relación entre el calcio coronario y las placas extracoronarias.
- La ecografía de los vasos extracoronarios puede servir como una valiosa herramienta de detección de la aterosclerosis coronaria en individuos asintomáticos de alto riesgo.
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