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Las células T CD4 + ayudan a controlar la memoria de las células T CD8 + a través de la muerte celular inducida por

Edith M Janssen1, Nathalie M Droin, Edward E Lemmens

  • 1Division of Cellular Immunology, La Jolla Institute for Allergy and Immunology, 10355 Science Center Drive, San Diego, California 92121, USA.

Nature
|March 4, 2005
PubMed
Resumen

La ayuda de las células T CD4+ durante el priming permite que las células T CD8+ se expandan de forma autónoma al volver a encontrarse con antígenos, formando una memoria inmune. Sin esta ayuda, las células T CD8+ sufren apoptosis mediada por TRAIL, lo que pone de relieve un nuevo mecanismo en la inmunidad adaptativa.

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