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Tratamiento de la funguria
A Wong-Beringer1, R A Jacobs, B J Guglielmo
1Division of Clinical Pharmacy, School of Pharmacy, University of California, San Francisco 94143-0622.
JAMA
|May 27, 1992
Resumen
El riego antifúngico de la vejiga, en particular la anfotericina B, es prometedor para la funguria sin complicaciones. Sin embargo, los diseños de estudio inconsistentes limitan las recomendaciones definitivas de tratamiento para las infecciones fúngicas del tracto urinario.
Área de la Ciencia:
- La micología de la micología.
- Enfermedades infecciosas Enfermedades infecciosas.
- Farmacología Farmacología.
Sus antecedentes:
- La funguria, o presencia de hongos en la orina, es una preocupación creciente, especialmente en los entornos de atención médica.
- La funguria sin complicaciones carece de directrices claras de tratamiento debido a la limitada evidencia de alta calidad.
Objetivo del estudio:
- Revisar y evaluar los tratamientos antifúngicos para la funguria sin complicaciones.
- Identificar agentes antifúngicos efectivos y evaluar el impacto de los factores de riesgo en los resultados del tratamiento.
Principales métodos:
- Revisión sistemática de informes de casos y estudios en inglés (1960-1991) sobre el tratamiento de la funguria sin complicaciones.
- Análisis del diseño del estudio, definiciones, regímenes de tratamiento, factores de riesgo y seguimiento del paciente.
Principales resultados:
- La comparación directa de los antifúngicos se vio obstaculizada por la heterogeneidad en las metodologías de estudio.
- La irrigación de la vejiga con anfotericina B pareció ser la más efectiva; el ketoconazol fue el menos efectivo.
- Los factores predisponentes como los catéteres urinarios influyen significativamente en el fracaso del tratamiento.
Conclusiones:
- La evidencia actual es insuficiente para recomendar un régimen de tratamiento específico para la funguria sin complicaciones.
- Se necesitan estudios prospectivos y bien controlados para establecer estrategias terapéuticas óptimas.
- Los casos sintomáticos requieren tratamiento, pero el mejor enfoque sigue siendo indeterminado.
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