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Updated: Jun 8, 2026

Novel RNA-Binding Proteins Isolation by the RaPID Methodology
11:19

Novel RNA-Binding Proteins Isolation by the RaPID Methodology

Published on: September 30, 2016

Bases estructurales para el reconocimiento específico del ARN guía por parte de la proteína de A. fulgidus Piwi

Jin-Biao Ma1, Yu-Ren Yuan, Gunter Meister

  • 1Structural Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

Nature
|April 1, 2005
PubMed
Resumen

El dominio PIWI en las proteínas argonautas es crucial para la regulación genética de la interferencia de ARN (RNAi). Este estudio revela la estructura cristalina de un complejo Piwi-RNA, detallando cómo la unión del ARN guía facilita el reconocimiento y la escisión del objetivo del ARN mensajero.

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