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No hay descanso para REST: REST/NRSF regulación de la neurogénesis
Victoria V Lunyak1, Michael G Rosenfeld1
1Department of Medicine, University of California, San Diego, Howard Hughes Medical Institute, La Jolla, California.
Cell
|May 24, 2005
Resumen
La regulación epigenética guía el desarrollo neuronal. El represor REST / NRSF es crucial para que las células pluripotentes se conviertan en progenitores neuronales, controlando la neurogénesis temprana.
Área de la Ciencia:
- La neurociencia es la neurociencia.
- Biología del desarrollo Biología del desarrollo.
- La epigenética es la epigenética.
Sus antecedentes:
- La adquisición y el mantenimiento de los rasgos neuronales están controlados por estrategias epigenéticas.
- Los represores y co-represores de la transcripción forman una red compleja para la especificidad génica.
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