Protocolo basado en la transformación de Fourier de matriz G basado en NOESY para la determinación de la estructura

Yang Shen1, Hanudatta S Atreya, Gaohua Liu

  • 1Department of Chemistry, The State University of New York at Buffalo, Buffalo, New York 14260, USA.

Resumen

Un nuevo protocolo de resonancia magnética nuclear (RMN) que utiliza la transformación de Fourier de matriz G (GFT) permite una determinación rápida y de alta calidad de la estructura de las proteínas. Este método asigna de manera eficiente las restricciones del Efecto Nuclear Overhauser (NOE) para proteínas de hasta 25 kDa, acelerando la investigación en biología estructural.

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