El mapeo de todo el cromosoma de la unión al receptor de estrógeno revela una regulación de largo alcance que

Jason S Carroll1, X Shirley Liu, Alexander S Brodsky

  • 1Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, 44 Binney Street, Boston, Massachusetts 02115, USA.

Cell
|July 13, 2005
PubMed
Resumen

Los sitios de unión al receptor de estrógeno (ER) fueron mapeados en los cromosomas humanos. La unión directa a ER requiere el factor de cabeza de horquilla FoxA1, que es esencial para la expresión génica inducida por estrógeno en el cáncer de mama.

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