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Cell Population Analyses During Skin Carcinogenesis
Published on: August 21, 2013
Incidencia de carcinomas de células basales y de células escamosas en una población menor de 40 años
Leslie J Christenson1, Theresa A Borrowman, Celine M Vachon
1Department of Dermatology, Mayo Clinic, Rochester, Minn 55905, USA.
JAMA
|August 11, 2005
Resumen
La incidencia de cáncer de piel no melanoma está aumentando en adultos jóvenes, particularmente el carcinoma de células basales en mujeres. Esta tendencia pone de relieve la necesidad urgente de estrategias de prevención del cáncer de piel dirigidas a poblaciones más jóvenes.
Área de la Ciencia:
- Dermatología Dermatología dermatología.
- Epidemiología La epidemiología.
- Oncología Oncología.
Sus antecedentes:
- La incidencia del cáncer de piel no melanoma (NMSC) está aumentando, especialmente en las poblaciones de edad avanzada.
- Existen datos limitados sobre la incidencia de NMSC en personas menores de 40 años.
Objetivo del estudio:
- Determinar las incidencias específicas por sexo y edad del carcinoma basocelular (BCC) y del carcinoma de células escamosas (SCC) en individuos menores de 40 años.
- Analizar las tendencias en la incidencia de BCC y SCC a lo largo del tiempo.
- Para describir la presentación clínica, la recurrencia, la metástasis y la histología de estos tumores en adultos jóvenes.
Principales métodos:
- Examen de caso de incidencia retrospectiva basado en la población.
- Utilizó registros médicos completos del condado de Olmsted, Minnesota a través del Proyecto de Epidemiología de Rochester.
- Se incluyeron pacientes menores de 40 años diagnosticados con CCB o CCS entre 1976 y 2003.
Principales resultados:
- 451 BCC y 70 SCC diagnosticados en individuos menores de 40 años.
- La incidencia de BCC aumentó significativamente en las mujeres (25.9/100.000) pero no en los hombres (20.9/100.000).
- La incidencia de SCC aumentó significativamente tanto en mujeres (3,9/100,000) como en hombres (3,9/100,000).
Conclusiones:
- La incidencia de NMSC está aumentando en adultos jóvenes en el condado de Olmsted, Minnesota.
- Se observó un aumento desproporcionado de BCC entre las mujeres jóvenes.
- Los hallazgos subrayan la importancia de la prevención del cáncer de piel para los adultos jóvenes debido a los posibles aumentos a largo plazo en la aparición de NMSC.
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