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Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer
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Cáncer colorrectal: mutaciones en una vía de señalización

D Williams Parsons1, Tian-Li Wang, Yardena Samuels

  • 1The Sidney Kimmel Comprehensive Cancer Center and The Howard Hughes Medical Institute, The Johns Hopkins University Medical Institutions, Baltimore, Maryland 21231, USA.

Nature
|August 12, 2005
PubMed
Resumen

Los investigadores identificaron mutaciones genéticas en las serina/treonina quinasas en los cánceres colorrectales humanos. Este descubrimiento pone de relieve la vía de la fosfatidilinositol-3-OH quinasa (PI(3) K) como un objetivo terapéutico potencial para el tratamiento del cáncer.

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