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Characterization of Multi-subunit Protein Complexes of Human MxA Using Non-denaturing Polyacrylamide Gel-electrophoresis
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Bases estructurales para la activación de la toxina del cólera por el ARF6-GTP humano

Claire J O'Neal1, Michael G Jobling, Randall K Holmes

  • 1Department of Chemistry, University of Washington, Seattle, WA 98195, USA.

Science (New York, N.Y.)
|August 16, 2005
PubMed
Resumen

La toxina del cólera explota los factores humanos de ADP-ribosilación (ARF) para causar enfermedades. Los estudios estructurales revelan cómo la unión de ARF altera la toxina, lo que le permite activar una proteína de señalización clave y causar diarrea.

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