Video Experimental Relacionado

Updated: Jul 17, 2026

Measurement of Heme Synthesis Levels in Mammalian Cells
09:43

Measurement of Heme Synthesis Levels in Mammalian Cells

Published on: July 9, 2015

La deficiencia de glutaredoxina 5 revela que los grupos de Fe-S son necesarios para la síntesis de hemo de los

Rebecca A Wingert1, Jenna L Galloway, Bruce Barut

  • 1Stem Cell Program and Division Hematology/Oncology Children's Hospital and Dana-Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|August 20, 2005
PubMed
Resumen

El conjunto de clúster de hierro-azufre (Fe-S) es crucial para la producción de hemoglobina. Este estudio revela que el deteriorado ensamblaje de racimos de Fe-S en el pez cebra activa la proteína reguladora del hierro 1 (IRP1), bloqueando la biosíntesis de hemo.

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