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El origen de la encefalopatía espongiforme bovina: la hipótesis de la enfermedad priónica humana
Alan C F Colchester1, Nancy T H Colchester
1Kent Institute of Medicine and Health Sciences, University of Kent, Canterbury CT2 7PD, UK. a.colchester@kent.ac.uk
Lancet (London, England)
|September 6, 2005
Resumen
El origen de la encefalopatía espongiforme bovina (ESB) puede estar relacionado con las enfermedades priónicas humanas. Una nueva teoría sugiere que el ganado fue infectado por vía oral a través de alimento animal contaminado, posiblemente del subcontinente indio.
Área de la Ciencia:
- Medicina Veterinaria La medicina veterinaria es el campo de la medicina en el que se desarrolla la medicina veterinaria.
- La neurociencia es la neurociencia.
- Epidemiología La epidemiología.
Sus antecedentes:
- La etiología de la encefalopatía espongiforme bovina (ESB) sigue siendo indeterminada.
- Las hipótesis anteriores, incluida la tembladera ovina y la esporádica encefalopatía espongiforme transmisible bovina (ETS), carecen de pruebas de apoyo definitivas.
Objetivo del estudio:
- Proponer una nueva teoría sobre el origen de la EEB.
- Investigar posibles rutas de transmisión y fuentes geográficas de la EEB.
Principales métodos:
- Formulación de una nueva teoría etiológica para la EEB.
- La hipótesis de la transmisión oral a través de alimentos para animales contaminados.
- La identificación del subcontinente indio como un potencial origen geográfico.
Principales resultados:
- El estudio propone tres hipótesis interconectadas para el origen de la EEB.
- Hipótesis 1: La EEB se originó a partir de una EET humana.
- Hipótesis 2: La infección se produjo por vía oral a través de alimentos para animales que contienen materiales de mamíferos contaminados, potencialmente de restos humanos.
Conclusiones:
- La teoría postula que los materiales de mamíferos importados del subcontinente indio pueden haber introducido EET humanos en el alimento para el ganado.
- Se requiere más investigación para examinar las fuentes de alimentos para animales y la transmisibilidad de las EET humanas al ganado.
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