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Updated: Jul 13, 2026
14:22
Free Radicals in Chemical Biology: from Chemical Behavior to Biomarker Development
Published on: April 15, 2013
"Atado" al trabajo: la hipótesis de la hormona libre revisada
1Burns and Allen Research Institute, Cedars-Sinai Medical Center, David Geffen School of Medicine at UCLA, University of California, Los angeles, CA 90048, USA.
Cell
|September 7, 2005
Resumen
Los animales que carecen de megalina, un receptor involucrado en la captación celular, muestran resistencia a las hormonas esteroides sexuales. Esto sugiere que la megalina juega un papel crucial en la mediación de los efectos de estas hormonas vitales.
Área de la Ciencia:
- Endocrinología Endocrinología.
- Biología celular Biología celular.
- Biología Molecular Biología Molecular
Sus antecedentes:
- Megalin es un receptor de superficie celular que pertenece a la familia de las proteínas relacionadas con el receptor de lipoproteínas de baja densidad (LRP).
- Los miembros de la familia LRP funcionan como receptores endocíticos para diversos ligandos extracelulares.
- Este estudio investiga el papel fisiológico de la megalina en relación con la acción de la hormona esteroide sexual.
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