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Las vías mediadas por apolipoproteínas de la presentación del antígeno lipídico

Peter van den Elzen1, Salil Garg, Luis León

  • 1Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|October 7, 2005
PubMed
Resumen

Las apolipoproteínas séricas, como la apolipoproteína E, entregan antígenos lipídicos exógenos a las moléculas CD1 en las células que presentan el antígeno, lo que permite la activación de las células T. Esto pone de relieve un vínculo crucial entre el metabolismo lipídico y las respuestas inmunes a los antígenos lipídicos.

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