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Updated: May 10, 2026

Isolation and Kv Channel Recordings in Murine Atrial and Ventricular Cardiomyocytes
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Published on: March 12, 2013

Aumento de la actividad de AMPK asociada a las subunidades alfa2 y cardiomiopatía PRKAG2

Ferhaan Ahmad1, Michael Arad, Nicolas Musi

  • 1Department of Genetics, Harvard Medical School, Howard Hughes Medical Institute, Boston, MA, USA.

Circulation
|November 9, 2005
PubMed
Resumen

Las mutaciones de PRKAG2 causan cardiomiopatía al activar la alfa2-AMPK, lo que lleva a la acumulación de glucógeno. La inhibición de la alfa2-AMPK en ratones revirtió las anomalías cardíacas y de conducción, identificando a la alfa2 como el mediador clave.

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