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Robert Koch: el abuelo de la clonación?
1Wohl Virion Centre, Division of Infection and Immunity, University College London, London W1T 4JF, United Kingdom.
Cell
|November 16, 2005
Resumen
Robert Koch, premio Nobel, fue pionero en las técnicas de clonación bacteriana. Sus métodos para aislar microbios como la tuberculosis, el ántrax y el cólera revolucionaron la microbiología y siguen siendo fundamentales para la investigación biológica.
Área de la Ciencia:
- Microbiología Microbiología.
- Bacteriología Bacteriología.
- Biología Molecular Biología Molecular
Sus antecedentes:
- Conmemorando el centenario del Premio Nobel de Robert Koch por la identificación de la bacteria de la tuberculosis.
- Destacando el trabajo fundamental de Koch en el aislamiento de microbios patógenos, incluidos los responsables del ántrax y el cólera.
- Subrayando la importancia a menudo pasada por alto del desarrollo de Koch de las técnicas de clonación bacteriana.
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01:09Recombinant DNA
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01:27Reproductive Cloning
Reproductive cloning is the process of producing a genetically identical copy—a clone—of an entire organism. While clones can be produced by splitting an early embryo—similar to what happens naturally with identical twins—cloning of adult animals is usually done by a process called somatic cell nuclear transfer (SCNT).
Somatic Cell Nuclear Transfer
In SCNT, an egg cell is taken from an animal and its nucleus is removed, creating an enucleated egg. Then a somatic cell—any cell that is not a sex...
Somatic Cell Nuclear Transfer
In SCNT, an egg cell is taken from an animal and its nucleus is removed, creating an enucleated egg. Then a somatic cell—any cell that is not a sex...
01:09Recombinant DNA
Overview
01:27Reproductive Cloning
Reproductive cloning is the process of producing a genetically identical copy—a clone—of an entire organism. While clones can be produced by splitting an early embryo—similar to what happens naturally with identical twins—cloning of adult animals is usually done by a process called somatic cell nuclear transfer (SCNT).
Somatic Cell Nuclear Transfer
In SCNT, an egg cell is taken from an animal and its nucleus is removed, creating an enucleated egg. Then a somatic cell—any cell that is not a sex...
Somatic Cell Nuclear Transfer
In SCNT, an egg cell is taken from an animal and its nucleus is removed, creating an enucleated egg. Then a somatic cell—any cell that is not a sex...
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01:08Cloning of Dolly the Sheep
The first successfully cloned mammal was Dolly, a sheep, born on 5th July 1996 at Roslin Institute, Scotland. The cloned sheep was named after the American singer Dolly Parton. Dolly lived for seven years and died of respiratory complications, which is speculated to be due to the actual age of her DNA. Because the DNA in cloned cells belongs to an older individual, the cloned individual’s life expectancy may be affected. Indeed, analysis of Dolly’s DNA revealed shorter telomeres than other...