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Estructura cristalina del factor de crecimiento transformador-beta 2: un pliegue inusual para la superfamilia

S Daopin1, K A Piez, Y Ogawa

  • 1Laboratory of Molecular Biology, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892.

Science (New York, N.Y.)
|July 17, 1992
PubMed
Resumen

La estructura cristalina del factor de crecimiento transformador-beta 2 (TGF-beta 2) revela un pliegue alargado estabilizado por enlaces disulfuro e interacciones hidrofóbicas. Esta estructura sugiere que otros miembros de la superfamilia TGF-beta comparten un pliegue similar, crucial para la regulación celular.

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