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Nuclear Magnetic Resonance Spectroscopy for the Identification of Multiple Phosphorylations of Intrinsically Disordered Proteins
12:47

Nuclear Magnetic Resonance Spectroscopy for the Identification of Multiple Phosphorylations of Intrinsically Disordered Proteins

Published on: December 27, 2016

Caracterización energética de péptidos polialaninos helicoidales cortos en agua: análisis de los datos de

Robert J Kennedy1, Sharon M Walker, Daniel S Kemp

  • 1Department of Chemistry, Massachusetts Institute of Technology, Cambridge, 02139, USA.

Journal of the American Chemical Society
|December 1, 2005
PubMed
Resumen

Este estudio cuantifica la propensión helicoidal de alanina (w(Ala) ((n)) en péptidos utilizando desplazamientos químicos de RMN. Los resultados muestran que los residuos de tert-leucina son moderadamente desestabilizadores de la hélice, lo que afecta la estabilidad de la hélice de alanina.

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