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La caseína quinasa 1 parejas gamma Wnt activación del receptor para la transducción de la señal citoplasmática

Gary Davidson1, Wei Wu, Jinlong Shen

  • 1Division of Molecular Embryology, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany. g.davidson@dkfz-heidelberg.de

Nature
|December 13, 2005
PubMed
Resumen

Los investigadores identificaron a la caseína quinasa 1 gamma (CK1gamma) como un regulador clave de la señalización de Wnt/beta-catenina. Este descubrimiento revela un mecanismo conservado que vincula la activación del receptor Wnt a la transducción de señales aguas abajo, crucial para el desarrollo embrionario y la enfermedad.

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