Search research articles

ACERCA DE JoVE

Visión General Liderazgo Blog Centro de Ayuda JoVE

AUTORES

Proceso de Publicación Consejo Editorial Alcance y Políticas Revisión por Pares Preguntas Frecuentes Enviar

BIBLIOTECARIOS

Testimonios Suscripciones Acceso Recursos Consejo Asesor de Bibliotecas Preguntas Frecuentes

INVESTIGACIÓN

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archivo

EDUCACIÓN

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Centro de Recursos para Profesores Sitio de Profesores

Términos y Condiciones de Uso

Política de Privacidad

Videos de Conceptos Relacionados

Induced-fit Model

Induced-fit Model

Most chemical reactions in cells require enzymes—biological catalysts that speed up the reaction without being consumed or permanently changed. They reduce the activation energy needed to convert the reactants into products. Enzymes are proteins, that usually work by binding to a substrate—a reactant molecule that they act upon.
Enzymes exhibit substrate specificity, meaning that they can only bind to certain substrates. This is mainly determined by the shape and chemical characteristics of...

Transgenic Organisms

Transgenic Organisms

Molecular Models

Molecular Models

Physical models representing molecular architectures of chemical compounds play essential roles in understanding chemistry. The use of molecular models makes it easier to visualize the structures and shapes of atoms and molecules.

Mouse Models of Cancer Study

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...

Transducer Mechanism: Enzyme-Linked Receptors

Transducer Mechanism: Enzyme-Linked Receptors

Enzyme-linked receptors are cell-surface receptors acting as an enzyme or associating with an enzyme intracellularly. They make excellent drug targets. Drugs can bind to the extracellular ligand-binding domain or directly affect their enzymatic domain and alter their activity.
Major types that are helpful drug targets include:

Microscopic Anatomy of Skeletal Muscles

Microscopic Anatomy of Skeletal Muscles

Skeletal muscle cells, also called muscle fibers, are distinctly elongated, multi-nucleated, slender biological units. They are packed with specialized structures designed to facilitate their primary function, which is contraction.
The muscle sarcolemma is a plasma membrane enclosing each muscle cell that conducts electrical signals called action potentials. The sarcolemma extends into the cell to form T-tubules, ensuring the neural impulses are uniformly distributed across the entire muscle...

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por

Same author

Two-way feedback between chromatin compaction and histone modification state explains <i>Saccharomyces cerevisiae</i> heterochromatin bistability.

Proceedings of the National Academy of Sciences of the United States of America·2024

Same author

Context-dependent function of the transcriptional regulator Rap1 in gene silencing and activation in <i>Saccharomyces cerevisiae</i>.

Proceedings of the National Academy of Sciences of the United States of America·2023

Same author

Two-way feedback between chromatin compaction and histone modification state explains <i>S. cerevisiae</i> heterochromatin bistability.

bioRxiv : the preprint server for biology·2023

Same author

Context dependent function of the transcriptional regulator Rap1 in gene silencing and activation in <i>Saccharomyces cerevisiae</i>.

bioRxiv : the preprint server for biology·2023

Same author

Limits to transcriptional silencing in Saccharomyces cerevisiae.

Genetics·2022

Same author

Distinct silencer states generate epigenetic states of heterochromatin.

Molecular cell·2022

Same journal

Co-option of lysosomal machinery shapes the evolution of the intracellular photosymbiosis supporting coral reefs.

Cell·2026

Same journal

LEF1 and niche factors determine T cell stemness across chronic diseases.

Cell·2026

Same journal

Recurrent patterns of TOP1-mediated neuronal genomic damage shared by major neurodegenerative disorders.

Cell·2026

Same journal

Four-dimensional molecular mapping from a spatial snapshot reveals the dynamics of hair follicle organogenesis.

Cell·2026

Same journal

Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data.

Cell·2026

Same journal

Systematic discovery of pathogen effector functions across human pathogens and pathways.

Cell·2026

Ver todos los artículos relacionados

Search research articles

Video Experimental Relacionado

Updated: May 11, 2026

In Vivo Modeling of the Morbid Human Genome using Danio rerio

In Vivo Modeling of the Morbid Human Genome using Danio rerio

Published on: August 24, 2013

Un atractivo organismo modelo de búsqueda.

Mark W Neff¹, Jasper Rine

¹Center for Veterinary Genetics, University of California, Davis, 95616, USA.

|January 28, 2006

Resumen

Este resumen es generado por máquina.

Los perros domésticos (Canis familiaris) muestran una rápida evolución a través de la cría selectiva. Los avances genómicos ahora permiten el estudio genético, ofreciendo información sobre la evolución canina, el desarrollo y el comportamiento.

Más Videos Relacionados

A Caenorhabditis elegans Model System for Amylopathy Study

A Caenorhabditis elegans Model System for Amylopathy Study

Published on: May 17, 2013

Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans

Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans

Published on: January 8, 2015

Videos de Experimentos Relacionados

Last Updated: May 11, 2026

In Vivo Modeling of the Morbid Human Genome using Danio rerio

In Vivo Modeling of the Morbid Human Genome using Danio rerio

Published on: August 24, 2013

A Caenorhabditis elegans Model System for Amylopathy Study

A Caenorhabditis elegans Model System for Amylopathy Study

Published on: May 17, 2013

Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans

Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans

Published on: January 8, 2015

Área de la Ciencia:

Genética La genética.
Biología evolutiva Biología evolutiva.
Comportamiento animal Comportamiento animal.

Sus antecedentes:

El perro doméstico (Canis familiaris) representa un modelo único para el estudio de procesos evolutivos rápidos.
La cría selectiva ha generado una notable diversidad en la forma y función canina.
Los recientes avances genómicos proporcionan herramientas poderosas para investigar la biología del perro.

Objetivo del estudio:

Para resaltar el potencial de Canis familiaris como un organismo modelo genéticamente tratable.
Explorar cómo los conocimientos genómicos pueden iluminar la evolución canina, el desarrollo y el comportamiento.

Principales métodos:

Aprovechando los avances en genómica canina.
Analizar datos genéticos para comprender las trayectorias evolutivas.
Integrar la información genómica con los estudios del desarrollo y el comportamiento.

Principales resultados:

Canis familiaris es ahora susceptible a una investigación genética detallada.
Los datos genómicos ofrecen una vía para comprender los mecanismos de la rápida evolución en los perros.
El estudio de la genética canina promete importantes conocimientos sobre los procesos biológicos fundamentales.

Conclusiones:

La tratabilidad genómica de Canis familiaris abre nuevas vías para el descubrimiento científico.
Comprender la evolución, el desarrollo y el comportamiento del perro a través de la genómica tiene amplias implicaciones.
El perro doméstico sirve como un poderoso modelo para la investigación de la biología evolutiva y del desarrollo.