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Estudio de la estructura y la dinámica de RMN de un heptapeptido formador de canales que se une a aniones y forma

Gabriel A Cook1, Robert Pajewski, Mahalaxmi Aburi

  • 1Departments of Biochemistry and Chemistry, Kansas State University, Manhattan, Kansas 66506, USA.

Journal of the American Chemical Society
|February 2, 2006
PubMed
Resumen

Este estudio detalla un péptido sintético que forma canales selectivos de cloruro, exhibiendo propiedades de apertura de voltaje. El análisis estructural revela que el péptido se une al cloruro a través de enlaces de hidrógeno y emparejamiento iónico, ofreciendo nuevos conocimientos sobre la función del canal aniónico sintético.

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