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Estructura de una glicosilasa de ADN que busca lesiones

Anirban Banerjee1, Webster L Santos, Gregory L Verdine

  • 1Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.

Science (New York, N.Y.)
|February 25, 2006
PubMed
Resumen

Las glicosilasas de ADN como MutM buscan activamente el ADN intacto insertando residuos de sonda y doblando pares de bases. Este mecanismo les permite localizar y eliminar de manera eficiente las nucleobases de ADN dañadas.

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