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Updated: Aug 9, 2026

A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
08:12

A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species

Published on: August 16, 2018

Adición altamente enantioselectiva de Me2Zn a los aldehídos catalizados por ClCr (Salen)

Pier Giorgio Cozzi1, Peter Kotrusz

  • 1Dipartimento di Chimica, University of Bologna, G. Ciamician, via Selmi 2, 40126 Bologna, Italy. piergiorgio.cozzi@unibo.it

Journal of the American Chemical Society
|April 13, 2006
PubMed
Resumen

Este estudio introduce un nuevo proceso enantioselectivo para la adición de dietilzinco (Me2Zn) a los aldehídos. El método, catalizado por ClCr(Salen), logra altos excesos enantioméricos (71-99%) bajo condiciones suaves.

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