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The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
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Decision Making01:20

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Decision-making is a fundamental cognitive process that involves evaluating alternatives and selecting among them. This process can range from simple choices, such as deciding what to wear, to complex decisions, like choosing a major in college or a career path. The complexity of the decision often dictates the approach we use, which can be broadly categorized into two types: automatic and controlled decision-making.
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Lazarus's Cognitive Appraisal Theory01:20

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Updated: Jul 6, 2026

Measuring the Subjective Value of Risky and Ambiguous Options using Experimental Economics and Functional MRI Methods
13:04

Measuring the Subjective Value of Risky and Ambiguous Options using Experimental Economics and Functional MRI Methods

Published on: September 19, 2012

Las neuronas en la corteza orbitofrontal codifican el valor económico.

Camillo Padoa-Schioppa1, John A Assad

  • 1Department of Neurobiology, Harvard Medical School, 220 Longwood Avenue, Boston, Massachusetts 02115, USA. camillo@alum.mit.edu

Nature
|April 25, 2006
PubMed
Resumen
Este resumen es generado por máquina.

Las neuronas en la corteza orbitofrontal (OFC) codifican el valor subjetivo durante la elección económica. Esta región del cerebro representa el valor de los bienes independientemente de los factores sensoriales o motores, lo que sugiere un papel clave en la toma de decisiones.

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Área de la Ciencia:

  • La neurociencia es la neurociencia.
  • Psicología Cognitiva Psicología cognitiva.
  • La economía del comportamiento es la economía del comportamiento.

Sus antecedentes:

  • La elección económica implica la selección entre opciones basadas en preferencias subjetivas.
  • Comprender la base neuronal de la representación del valor en la toma de decisiones es crucial.
  • La corteza orbitofrontal (OFC) está implicada en la toma de decisiones basadas en valores, pero su papel preciso es objeto de debate.

Objetivo del estudio:

  • Para investigar cómo las neuronas en la corteza orbitofrontal (OFC) representan el valor durante la elección económica.
  • Para determinar si la actividad OFC codifica valores independientemente de los parámetros sensoriales o motores.

Principales métodos:

  • Grabaciones electrofisiológicas de neuronas de la corteza orbitofrontal en monos durante una tarea de elección basada en valores.
  • Presentación de diferentes bienes con diferentes valores subjetivos.
  • Análisis de la actividad neuronal en relación con los bienes ofrecidos, los bienes elegidos y los parámetros de la tarea.

Principales resultados:

  • Las neuronas de la corteza orbitofrontal (OFC) codifican robustamente el valor de los bienes ofrecidos y elegidos.
  • La representación de valor en el OFC es independiente de la ubicación espacial de los bienes y las respuestas motoras.
  • Esta independencia distingue la función OFC de otras áreas del cerebro involucradas en el procesamiento sensorial o motor.

Conclusiones:

  • La corteza orbitofrontal (OFC) juega un papel crítico en la asignación de valor subjetivo a las opciones durante la elección económica.
  • Las neuronas OFC parecen representar el valor de los bienes, apoyando un marco en el que la elección económica se trata principalmente de elegir entre bienes.
  • Estos hallazgos proporcionan una base neuronal para la comprensión del cálculo de valor en la toma de decisiones y tienen implicaciones para los modelos psicológicos de elección.