Chaperones moleculares y control de calidad de las proteínas.

Bernd Bukau1, Jonathan Weissman, Arthur Horwich

  • 1Zentrum fur Molekulare Biologie, Universität Heidelberg, 69120 Heidelberg, Germany.

Cell
|May 9, 2006
PubMed
Resumen

El control de calidad de las proteínas celulares combate el mal plegamiento y la agregación utilizando estrategias sofisticadas. Los hallazgos recientes destacan la eliminación de agregados, los mecanismos del retículo endoplasmático y las chaperonas moleculares como las Hsp70 y las AAA + unfoldases.

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