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Abrupta retirada ambulatoria de la medicación en pacientes con migraña que abusan de los analgésicos
1Princess Margaret Migraine Clinic, Charing Cross Hospital, London, UK.
Lancet (London, England)
|June 15, 1991
Resumen
La retirada abrupta de los analgésicos en pacientes con dolor de cabeza crónico diario con migraña redujo efectivamente el uso excesivo de medicamentos. La mayoría de los pacientes experimentaron alivio del dolor de cabeza y el uso normalizado de analgésicos dentro de los seis meses.
Área de la Ciencia:
- Neurología Neurología.
- Farmacología Farmacología.
Sus antecedentes:
- El uso excesivo de medicamentos es una causa común de dolor de cabeza crónico diario en las personas con migraña.
- Identificar y tratar el abuso de medicamentos es crucial para el manejo de los trastornos crónicos de dolor de cabeza.
Objetivo del estudio:
- Evaluar la eficacia de la retirada abrupta de la medicación en el tratamiento del dolor de cabeza crónico diario secundario al abuso de medicamentos en pacientes con migraña.
- Evaluar los resultados a largo plazo de esta estrategia de tratamiento.
Principales métodos:
- Se incluyeron 46 pacientes con migraña con dolor de cabeza crónico diario debido al abuso de medicamentos.
- El tratamiento incluía la abrupta retirada del medicamento, la educación del paciente, el seguimiento regular, la amitriptilina y el naproxeno para aliviar los síntomas.
Principales resultados:
- 37 de 46 pacientes (80%) lograron alivio de los dolores de cabeza crónicos y normalizaron su ingesta de analgésicos a los 6 meses.
- 6 pacientes mostraron una reducción en la ingesta de analgésicos pero ningún cambio en la gravedad del dolor de cabeza.
- 2 pacientes no redujeron la ingesta, y 1 paciente se retiró del estudio.
Conclusiones:
- La retirada abrupta de los medicamentos ofensivos, combinada con la atención de apoyo y la farmacoterapia adecuada, es un tratamiento eficaz para el dolor de cabeza diario crónico en migrañeros con uso excesivo de medicamentos.
- Este enfoque puede conducir a un alivio significativo del dolor de cabeza y la normalización del uso de medicamentos.
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