Video Experimental Relacionado
Updated: Jul 15, 2026
11:17
Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Cambios en la lista de medicamentos esenciales de la Organización Mundial de la Salud
1Management Sciences for Health, Boston, MA 02130.
Lancet (London, England)
|September 21, 1991
Resumen
La Organización Mundial de la Salud es la Organización Mundial de la Salud.
Área de la Ciencia:
- Política Farmacéutica y Economía de la Salud
- Investigación de uso de drogas Investigación de uso de drogas.
Sus antecedentes:
- La Lista Modelo de Medicamentos Esenciales de la Organización Mundial de la Salud (OMS) proporciona pautas cruciales para la selección de productos farmacéuticos.
- La lista tiene como objetivo garantizar el acceso a medicamentos seguros y efectivos a nivel mundial.
Objetivo del estudio:
- Analizar la evolución de la Lista Modelo de Medicamentos Esenciales de la OMS desde 1977 hasta 1990.
- Evaluar las razones de los cambios en la composición de la lista a lo largo del tiempo.
Principales métodos:
- Análisis comparativo de seis ediciones de la Lista Modelo de Medicamentos Esenciales de la OMS (1977-1990).
- Cuantificación de las adiciones y supresiones de fármacos.
- Categorización de los nuevos fármacos en función de las entidades o indicaciones clínicas.
Principales resultados:
- El número de medicamentos esenciales aumentó de 205 a 268 entre 1977 y 1990.
- Se agregaron 120 drogas y se eliminaron 57 durante este período.
- Sólo 16 de los fármacos añadidos representaban nuevas entidades clínicas o indicaciones; la mayoría de las adiciones reflejaban cambios en la utilidad percibida del fármaco.
Conclusiones:
- La Lista Modelo de Medicamentos Esenciales de la OMS se ha expandido significativamente, impulsada más por cambios en la percepción de los medicamentos que por la innovación científica.
- A pesar de los cambios, la lista sigue siendo un recurso valioso para los procesos nacionales de selección de medicamentos.
Videos de Conceptos Relacionados
01:17Drug Nomenclature
During the development of a new pharmaceutical, the manufacturer initially assigns a code name to the drug. Once approved, the drug receives a United States Adopted Name (USAN)—a generic, nonproprietary designation. Upon being listed in the United States Pharmacopeia, this nonproprietary name becomes the drug's official name. Additionally, the manufacturer assigns a proprietary name or trademark, which serves as the brand name under which the drug is marketed. It is worth noting that the same...
01:25Drug Classes and Categories
Drugs can be classified according to their chemical composition or their intended therapeutic application. For instance, anti-infective agents that possess the ability to eliminate pathogens or suppress their growth and reproduction can be grouped based on the organisms they target or their chemical structure. Furthermore, drugs can be divided into prescription, nonprescription, or controlled substances. Prescription medications, such as antibiotics, require oversight from a licensed healthcare...
01:02Prescription, Nonprescription and Orphan Drugs
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
01:28Drug Products: Biologics, Biosimilars and Interchangeables
Biologics, derived from living sources such as humans, animals, or microorganisms, represent a significant category of pharmaceuticals. These complex molecules, developed through advanced biotechnological methods or purified from natural sources, include essential medical treatments like insulin and growth hormones. The complexity of biologics arises from their large molecular structures and the intricate processes required for their production, making them distinct from conventional...
01:26Pharmaceutical Equivalents
As defined by regulatory standards, pharmaceutical equivalents require generic drug products to have identical dosage forms and chemically identical active pharmaceutical ingredients (APIs). They must adhere to compendial or applicable standards for potency, content uniformity, disintegration times, and dissolution rates. In the case of modified-release dosage forms, variations in drug content are permissible as long as the delivered amount remains consistent with the innovator drug product.
01:26FDA Approved Drugs: Changes to Approved Drugs
Post-approval, manufacturers may modify an approved new or generic drug product. Such modifications can encompass alterations in the Active Pharmaceutical Ingredient (API), manufacturing process, formulation, batch size, manufacturing site, and container closure system (FDA Guidance for Industry, April 2004). Often, a drug product may undergo multiple changes.These modifications require careful evaluation to determine their potential impact on the drug product's identity, strength, quality,...