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Updated: Jul 16, 2026

Development of Stem Cell-derived Antigen-specific Regulatory T Cells Against Autoimmunity
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Published on: November 8, 2016

El paradigma a prueba de fallos de la auto-tolerancia inmunológica

G Kroemer1, C Martínez

  • 1Centro de Biología Molecular del CSIC, Universidad Autómoma de Madrid, Spain.

Lancet (London, England)
|November 16, 1991
PubMed
Resumen

La autotolerancia inmunológica se basa en múltiples capas de defensa, incluida la deleción clonal, la inactivación y la supresión. El fallo de todos estos sistemas puede conducir a enfermedades autoinmunes, lo que pone de relieve un mecanismo jerárquico de seguridad ante fallas.

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