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Prevención del herpes labial inducido por la luz ultravioleta con protector solar
J F Rooney1, Y Bryson, M L Mannix
1Laboratory of Oral Medicine, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland 20892.
Lancet (London, England)
|December 7, 1991
Resumen
La exposición a la luz solar puede desencadenar herpes labial recurrente. La aplicación de protector solar antes de la exposición a la luz ultravioleta (UV) evitó efectivamente la reactivación del dolor de frío en un ensayo clínico.
Área de la Ciencia:
- Dermatología Dermatología dermatología.
- Virología Virología.
- La fotomedicina es la fotomedicina.
Sus antecedentes:
- El herpes labial recurrente a menudo es precedido por la exposición a la luz solar.
- La radiación ultravioleta (UV) B es un desencadenante conocido para la reactivación del virus del herpes simple (HSV).
Objetivo del estudio:
- Evaluar la eficacia de un bloqueador solar en la prevención de la reactivación inducida por la luz UV del herpes labial recurrente.
- Evaluar el papel del protector solar en el manejo de brotes de herpes labial desencadenados por la luz solar.
Principales métodos:
- Se llevó a cabo un ensayo cruzado doble ciego, controlado con placebo.
- 38 pacientes con antecedentes de herpes labial recurrente fueron expuestos a la luz UV en dos ocasiones.
- El protector solar o un placebo se aplicó a los labios antes de la exposición a los rayos UV.
Principales resultados:
- El herpes labial se desarrolló en el 71% de los pacientes después del placebo y la exposición a los rayos UV (tiempo promedio de recurrencia: 2,9 días).
- No se desarrollaron lesiones de herpes labial cuando se aplicó protector solar antes de la exposición a los rayos UV.
- Sólo un paciente arrojó HSV en el sitio de exposición después de la aplicación de protector solar.
Conclusiones:
- La luz UV es un potente estímulo para la reactivación del herpes labial.
- La aplicación tópica de protector solar parece ser eficaz en la prevención de las infecciones recurrentes de herpes labial inducidas por la luz solar.
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