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Incidencia, causa y resultado a corto plazo del status epilepticus convulsivo en la infancia: estudio prospectivo
Richard F M Chin1, Brian G R Neville, Catherine Peckham
1Neurosciences Unit, Institute of Child Health, University College London, and Great Ormond Street Hospital for Children NHS Trust, London, UK. r.chin@ich.ucl.ac.uk
Lancet (London, England)
|July 18, 2006
Resumen
El estado convulsivo epiléptico infantil (CSE) es una emergencia común con aspectos pediátricos únicos. Este estudio encontró que la CSE es más frecuente y menos letal en niños que en adultos, lo que informa sobre un mejor manejo.
Área de la Ciencia:
- Neurología Pediátrica.
- Epidemiología La epidemiología.
- Medicina de emergencia Medicina de emergencia.
Sus antecedentes:
- El estado convulsivo epiléptico (CSE) es una emergencia neurológica pediátrica líder.
- Los datos existentes, principalmente de poblaciones adultas, pueden no reflejar con precisión la ECE infantil.
- El Estudio de Estatus Epilepticus en el Norte de Londres en el Estudio de Vigilancia Infantil (NLSTEPSS) se inició para proporcionar una perspectiva pediátrica.
Objetivo del estudio:
- Para determinar la incidencia y las características de la infancia CSE.
- Establecer una comprensión pediátrica única del CSE.
- Informar sobre el manejo clínico y la asignación de recursos para el CSE pediátrico.
Principales métodos:
- Un estudio prospectivo de vigilancia basado en la población en el norte de Londres.
- Datos recopilados a través de una red clínica utilizando proformas estandarizadas y registros médicos.
- Modelado de captura-recaptura utilizado para estimar la determinación.
Principales resultados:
- La determinación estimada de los episodios de ECE está entre el 62% y el 84%.
- Incidencia ajustada a las constataciones de 17 a 23 episodios por cada 100.000 niños al año.
- La tasa de recurrencia en un año es del 16%; la tasa de mortalidad es del 3%.
Conclusiones:
- La EEC infantil es más común y menos fatal que en los adultos.
- Las causas de la EEC pediátrica difieren de las de las poblaciones adultas.
- Los datos pediátricos son cruciales para una gestión efectiva de la EEC y la asignación de recursos.
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