Inmovilización covalente regioselectiva y quimioselectiva de proteínas a través de aminoácidos no naturales

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Updated: Jul 20, 2026

Genetic and Biochemical Approaches for In Vivo and In Vitro Assessment of Protein Oligomerization: The Ryanodine Receptor Case Study
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Genetic and Biochemical Approaches for In Vivo and In Vitro Assessment of Protein Oligomerization: The Ryanodine Receptor Case Study

Published on: July 27, 2016

Cécile Gauchet1, Guillermo R Labadie, C Dale Poulter

  • 1Department of Chemistry, University of Utah, 315 South 1400 East, Room 2020, Salt Lake City, Utah 84112, USA.

Journal of the American Chemical Society
|July 20, 2006
PubMed
Resumen

Los investigadores desarrollaron un método versátil para unir covalentemente proteínas a superficies utilizando aminoácidos no naturales y química de clic o ligadura de Staudinger. Esta técnica de inmovilización de proteínas asegura estabilidad y amplia aplicabilidad.

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