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Updated: May 7, 2026
07:38
Quantifying the Activity of cis-Regulatory Elements in the Mouse Retina by Explant Electroporation
Published on: June 28, 2011
Desdibujando cis y trans en la regulación génica
Fabio Savarese1, Rudolf Grosschedl
1Max Planck Institute of Immunobiology, 79108 Freiburg, Germany.
Cell
|July 29, 2006
Resumen
Un solo potenciador puede controlar múltiples genes de receptores de olor (OR), lo que explica cómo las neuronas sensoriales olfativas seleccionan solo un gen de más de 1000. Este descubrimiento arroja luz sobre los complejos mecanismos de la expresión génica de los receptores olfativos.
Área de la Ciencia:
- Genética La genética.
- La neurociencia es la neurociencia.
- Biología Molecular Biología Molecular
Sus antecedentes:
- Las neuronas sensoriales olfativas (OSN) expresan un vasto repertorio de más de 1000 genes de receptores olfativos (OR).
- El mecanismo preciso por el cual los OSN logran la expresión monoalélica de un solo gen OR sigue siendo una cuestión clave en la investigación olfativa.
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