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Updated: Jul 6, 2026

Techniques to Induce and Quantify Cellular Senescence
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El envejecimiento de las células madre modificado por el inhibidor de la cinasa dependiente de ciclina p16INK4aa

Viktor Janzen1, Randolf Forkert, Heather E Fleming

  • 1Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Medical School, 185 Cambridge Street, Boston, Massachusetts 02114, USA.

Nature
|September 8, 2006
PubMed
Resumen

El envejecimiento de las células madre afecta a la reparación de los tejidos. La inhibición de p16INK4a en células madre hematopoyéticas (HSC) mejoró su función y tolerancia al estrés, ofreciendo una estrategia potencial para combatir el deterioro relacionado con la edad.

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