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Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes
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LFA-3, CD44 y CD45: desencadenantes fisiológicos de la liberación de TNF y IL-1 del monocito humano

D S Webb1, Y Shimizu, G A Van Seventer

  • 1Food and Drug Administration, Division of Cytokine Biology, Bethesda, MD 20892.

Science (New York, N.Y.)
|September 14, 1990
PubMed
Resumen

Las glicoproteínas monocíticas como LFA-3, CD44 y CD45, cuando se activan, desencadenan la liberación de citoquinas inmunorreguladoras del factor de necrosis tumoral alfa e interleucina-1 beta. Esto sugiere que las interacciones de adhesión celular señalan la liberación de monokinas.

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