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La señalización RalB: un puente entre la inflamación y el cáncer

Alberto Mantovani1, Frances Balkwill

  • 1Istituto Clinico Humanitas, Via Manzoni 56, 20089 Rozzano and University of Milan, Italy. alberto.mantovani@humanitas.it

Cell
|October 5, 2006
PubMed
Resumen

La RalB GTPasa vincula la inflamación y la señalización del cáncer mediante la regulación de TBK1. Esta vía inhibe la apoptosis de las células tumorales y estimula la inmunidad innata en las células normales.

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