La regulación de INK4/ARF en el cáncer y el envejecimiento

William Y Kim1, Norman E Sharpless

  • 1Department of Medicine, The University of North Carolina School of Medicine, Chapel Hill, 27599, USA.

Cell
|October 24, 2006
PubMed
Resumen

La pérdida del locus INK4a/ARF/INK4b es común en el cáncer. Sus productos, p16 ((INK4a), ARF y p15 ((INK4b), son cruciales para la supresión de tumores e influyen en el envejecimiento.

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