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Updated: May 7, 2026

Identification of Kinase-substrate Pairs Using High Throughput Screening
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Identification of Kinase-substrate Pairs Using High Throughput Screening

Published on: August 29, 2015

Caracterización de dos proteínas de 85 kd que se asocian con las receptoras de las tirosinacinasas, los complejos

M Otsu1, I Hiles, I Gout

  • 1Ludwig Institute for Cancer Research, London, England.

Cell
|April 5, 1991
PubMed
Resumen

La fosfatidilinositol 3-kinasa (PI3-kinasa) del cerebro bovino incluye 85 kDa de proteínas (p85 alfa/beta) con dominios SH2. Estas proteínas se unen a las tirosinacinasas pero carecen de actividad de la PI3-cinasa, lo que sugiere un papel regulador en las vías de señalización.

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