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A11-positive β-amyloid Oligomer Preparation and Assessment Using Dot Blotting Analysis
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La inhibición de la fibrilización beta-amiloide por la evolución dirigida de una hoja beta que presenta una proteína

Thaddeus J Smith1, Cliff I Stains, Scott C Meyer

  • 1Department of Chemistry, University of Arizona, Tucson, Arizona 85721, USA.

Journal of the American Chemical Society
|November 9, 2006
PubMed
Resumen

Los investigadores desarrollaron una nueva proteína de hoja beta en miniatura, TJ10, que efectivamente se dirige e inhibe los oligómeros beta-amiloides relacionados con la enfermedad de Alzheimer. Esta proteína es prometedora como estrategia terapéutica para las enfermedades amiloidogénicas.

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